Irritability in Autism in Children and Adolescents

October 23, 2023

Approximately 20% of patients with autism spectrum disorder have irritability.  Signs of autism related irritability include aggression, self-harming behavior, severe tantrums, emotional meltdowns, and need for isolation.

Currently, there are limited treatment options available for irritability associated with autism spectrum disorders.

I am particularly excited about the science behind a potential new treatment from Axial Therapeutics, AB-2004, for the improvement of irritability associated with autism. Axial’s innovative scientific approach builds on research which shows that substances produced by bacteria found in the gut can reach the brain and have a negative impact on neurological development and behavior.

AB-2004 works by reducing substances produced by bacteria commonly found in the gut before they enter the bloodstream and reach the brain.

I am currently conducting a clinical research study sponsored by Axial with AB-2004 in Las Vegas for adolescents who have autism spectrum disorder and irritability.

For more information about this study, call my office at 702-838-0742 or click here!

About Us

Dr. Childress is a world renowned psychiatrist specializing in ADHD and Autism. She has been in clinical research for over 20 years with more than 80 published articles.  Dr. Lampert is a pediatrician with 25 years of experience. She has always had a special interest in behavioral and developmental problems. If you believe your child suffers from ADHD, contact us today!


The Center for Psychiatry and Behavioral Medicine Inc is made up of 4 clinical research coordinators, 1 clinical research recruiter, and 1 medical receptionist. Our tiny but mighty team are all eager to help ensure you and your child get the best treatment you deserve!

Contact Information

Center for Psychiatry and Behavioral Medicine Inc. 702-838-0742